Subject    :    [2017 Apr;41(2)] Association between Blood Mercury Level and Visceral Adiposity in Adults
Writer KDA
Date 2017-07-06 11:00:12 Hit 6,337
Diabetes Metab J. 2017 Apr;41(2):113-120. English.
Published online Dec 21, 2016. 
Copyright © 2017 Korean Diabetes Association
Association between Blood Mercury Level and Visceral Adiposity in Adults
Jong Suk Park,1 Kyoung Hwa Ha,2,3 Ka He,4 and Dae Jung Kim2,3
1Department of Endocrinology and Metabolism, Yonsei University College of Medicine, Seoul, Korea.
2Cardiovascular and Metabolic Disease Etiology Research Center, Ajou University School of Medicine, Suwon, Korea.
3Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
4Department of Epidemiology and Biostatistics, Indiana University Bloomington School of Public Health, Bloomington, IN, USA.

Corresponding author: Dae Jung Kim. Department of Endocrinology and Metabolism, Ajou University School of Medicine, 164 World cup-ro, Yeongtong-gu, Suwon 16499, Korea. Email: 
Received May 25, 2016; Accepted August 16, 2016.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.



Few studies have examined the association between mercury exposure and obesity. The aim of this study is to investigate the association between blood mercury concentrations and indices of obesity in adults.


A total of 200 healthy subjects, aged 30 to 64 years, who had no history of cardiovascular or malignant disease, were examined. Anthropometric and various biochemical profiles were measured. Visceral adipose tissue (VAT) was measured using dual-energy X-ray absorptiometry (DXA).


All subjects were divided into three groups according to blood mercury concentrations. Compared with the subjects in the lowest tertile of mercury, those in the highest tertile were more likely to be male; were current alcohol drinkers and smokers; had a higher body mass index (BMI), waist circumference (WC), and VAT; had higher levels of blood pressure, fasting glucose, and insulin resistance; and consumed more fish. The blood mercury concentration was significantly associated with anthropometric parameters, showing relationships with BMI, WC, and VAT. After adjusting for multiple risk factors, the odds ratios (ORs) for high mercury concentration was significantly higher in the highest VAT tertile than in the lowest VAT tertile (OR, 2.66; 95% confidence interval, 1.05 to 6.62; P


The blood mercury concentration was significantly associated with VAT in healthy adults. Further studies are warranted to confirm our findings.

Body mass index; Intra-abdominal fat; Mercury; Obesity; Waist circumference

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