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| The Effect of 12 Weeks Aerobic, Resistance, and Combined Exercises on Omentin-1 Levels and Insulin Resistance among Type 2 Diabetic Middle-Aged Women |
Zeinab AminiLari,1 Mohammad Fararouei , 2 Sasan Amanat,3 Ehsan Sinaei,4 Safa Dianatinasab,3Mahmood AminiLari,1 Nima Daneshi,5 and Mostafa Dianatinasab2,5 |
| 1Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. |
| 2Shiraz HIV/AIDS Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. |
| 3Department of Nutrition, Shiraz University of Medical Sciences School of Nutrition and Food Sciences, Shiraz, Iran. |
| 4Department of Physical Therapy, Shiraz University of Medical Sciences School of Rehabilitation Sciences, Shiraz, Iran. |
| 5Department of Epidemiology, Student Research Committee, Shiraz University of Medical Sciences School of Health, Shiraz, Iran. |
Corresponding authors: Mostafa Dianatinasab. Shiraz HIV/AIDS Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Email: dianati.epid@gmail.com Corresponding authors: Mohammad Fararouei. Shiraz HIV/AIDS Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Email: fararooei@gmail.com
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Received May 29, 2016; Accepted January 09, 2017.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract
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Background
Recent studies have shown that omentin-1 derived from adipokines can affect physiological regulations and some metabolic dis-eases such as type 2 diabetes mellitus (T2DM).
Methods
The purpose of this study was to examine the impact of 12 weeks of aerobic (cycle ergometer), resistance, and combined exercises on omentin-1 level, glucose and insulin resistance indices in overweight middle age women with T2DM. In this study, 60 overweight middle age diabetic women were selected using simple random sampling and they were assigned to three groups of aerobic exercise (n=12), resistant exercise (n=12) and combined exercise (n=13), and one control group (n=15). Exercises were done in a three times per week sessions for a total of 12 weeks. Blood samples were collected before each exercise session and 24 hours after of the last session.
Results
Present study showed that fasting blood sugar decreased significantly in all intervention groups, while homeostasis model assessment of insulin resistance (HOMA-IR) decreased only in the aerobic and combined exercises groups. Furthermore, there was a significant increase in the omentin-1 level only in the combined exercise group.
Conclusion
Compared to aerobic and resistance exercises, 12 weeks of combined exercise was more efficient in improving HOMA-IR and increasing serum omentin-1 among women with T2DM.
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Keywords:
Diabetes mellitus, type 2; Exercise; Glucose; Insulin resistance; Omentin-1; Overweight women
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