Subject    :    [2019 Apr;43(2)] The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
Writer KDA
Date 2019-04-18 10:33:16 Hit 1,456
LINK URL https://e-dmj.org/search.php?where=aview&id=10.4093/dmj.2018.0039&code=2004DMJ&vmode=FULL (Click 24)
   
Diabetes Metab J. 2019 Apr;43(2):206-221. English.
Published online Dec 27, 2018.  https://doi.org/10.4093/dmj.2018.0039 
Copyright © 2019 Korean Diabetes Association
   
The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
Jung-Hwan Cho,1,* Eun-Jung Rhee,1,* Se-Eun Park,1 Hyemi Kwon,1 Jin-Hyung Jung,2 Kyung-Do Han,2Yong-Gyu Park,2 Hye Soon Park,3 Yang-Hyun Kim,4 Soon-Jib Yoo,5 Won-Young Lee,1 and on behalf of Taskforce Team of the Obesity Fact Sheet of the Korean Society for the Study of Obesity
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
2Department of Biostatistics, Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.
3Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
4Department of Family Medicine, Korea University College of Medicine, Seoul, Korea.
5Division of Endocrinology and Metabolism, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.

Corresponding authors: Won-Young Lee. Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea. Email: drlwy@hanmail.net Corresponding author: Soon-Jib Yoo. Division of Endocrinology and Metabolism, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 327 Sosa-ro, Wonmi-gu, Bucheon 14647, Korea. Email: sjyoo@catholic.ac.kr

 

*Jung-Hwan Cho and Eun-Jung Rhee contributed equally to this study as first authors.
 
Received February 25, 2018; Accepted September 03, 2018.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

 
Abstract

Background

Waist circumference (WC) is a well-known obesity index that predicts cardiovascular disease (CVD). We studied the relationship between baseline WC and development of incident myocardial infarction (MI) and ischemic stroke (IS) using a nationwide population-based cohort, and evaluated if its predictability is better than body mass index (BMI).

Methods

Our study included 21,749,261 Koreans over 20 years of age who underwent the Korean National Health Screening between 2009 and 2012. The occurrence of MI or IS was investigated until the end of 2015 using National Health Insurance Service data.

Results

A total of 127,289 and 181,637 subjects were newly diagnosed with MI and IS. The incidence rate and hazard ratio of MI and IS increased linearly as the WC level increased, regardless of adjustment for BMI. When the analyses were performed according to 11 groups of WC, the lowest risk of MI was found in subjects with WC of 70 to 74.9 and 65 to 69.9 cm in male and female, and the lowest risk of IS in subjects with WC of 65 to 69.9 and 60 to 64.9 cm in male and female, respectively. WC showed a better ability to predict CVD than BMI with smaller Akaike information criterion. The optimal WC cutoffs were 84/78 cm for male/female for predicting MI, and 85/78 cm for male/female for predicting IS.

Conclusion

WC had a significant linear relationship with the risk of MI and IS and the risk began to increase from a WC that was lower than expected.

   
Keywords:
Body mass indexCardiovascular diseasesCohort studiesNational Health ProgramsObservational studyWaist circumference

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