5 :: KDA, Korean Diabetes Association ::
string(8) "resource"
Subject    :    [2015 Oct;39(5)] Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers
Writer KDA
Date 2015-12-08 10:20:03 Hit 6,365
Diabetes Metab J. 2015 Oct;39(5):434-438. English. Published online Oct 22, 2015.  http://dx.doi.org/10.4093/dmj.2015.39.5.434 
Copyright © 2015 Korean Diabetes Association
   
Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers
Tomoyuki Kawada
Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan.
Corresponding author: Tomoyuki Kawada. Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bukyo-Ku, Tokyo 113-8602, Japan. Email: kawada@nms.ac.jp 
 
Received March 23, 2015; Accepted May 26, 2015.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

 
Abstract
Background

Confirmation regarding the association between impaired fasting glucose (IFG) and biomarkers in addition to metabolic components and lifestyle factors are required in the occupational filed for preventing diabetes mellitus.

Methods

The study was performed in working men aged 30 to 60 years old, who were not taking medication for any metabolic diseases. The author measured the serum levels of high-sensitivity C-reactive protein (CRP), uric acid, and plasma fibrinogen as potential biomarkers of IFG.

Results

The mean serum uric acid, log-transformed serum CRP, and plasma fibrinogen levels were higher in the subjects with IFG than in those without IFG. Multivariate analysis revealed significant associations between the presence of IFG and age, log-transformed value of serum CRP, increased waist circumference, hypertension, and hypertriglyceridemia, with odds ratios of 1.1 (95% confidence interval [CI], 1.08 to 1.1;P P PP

Conclusion

Serum CRP, age, and three metabolic components were associated with IFG. In contrast, there were no significant associations between IFG and lifestyle factors, serum uric acid or plasma fibrinogen.

   

Keywords: C-reactive protein, Fibrinogen, Impaired fasting glucose, Life style, Metabolic components.

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