Diabetes & Metabolism Journal (DMJ) is an international, peer-reviewed, open access, online and print journal aiming at publishing original research, reviews, and commentaries on all areas related to diabetes mellitus and metabolism. It is published bimonthly, with articles in English accepted through the process of peer review. Considering your research in related areas, we cordially invite you to submit a paper to DMJ.
Eun-Sun Jin, Jee-Seon Shim, Sung Eun Kim, Jae Hyun Bae, Shinae Kang, Jong Chul Won, Min-Jeong Shin, Heung Yong Jin, Jenny Moon, Hokyou Lee, Hyeon Chang Kim, In-Kyung Jeong, on Behalf of the Committee of Public Relation of the Korean Society of Lipid and Atherosclerosis
Diabetes & Metabolism Journal 2023;47(5):632-642.
This study aimed to investigate the prevalence and status of dyslipidemia management among South Korean adults under the name of the Dyslipidemia Fact Sheet 2022. The lipid profiles, age-standardized and crude prevalence, management status of hypercholesterolemia and dyslipidemia, and health behaviors were analyzed in Korean adults aged ≥20 years, using the Korea National Health and Nutrition Examination Survey data between 2007 and 2020. The crude prevalence of hypercholesterolemia in 2020 was 24%, the crude treatment rate was 55.2%, and the control rate was 47.7%. The crude prevalence of dyslipidemia was 40.2% between 2016 and 2020. However, it increased to 48.2% when the definition of hypo-HDL-cholesterolemia in women changed from <40 to <50 mg/dL.
Nikolai N. Scherbak, Robert Kruse, Thomas Nyström, Johan Jendle
Diabetes & Metabolism Journal 2023;47(5):668-681.
This study explored the impact of two glucose-lowering drugs, glimepiride and liraglutide, on circulating microRNAs (miRNAs) in individuals with type 2 diabetes. Glimepiride treatment altered the expression of specific miRNAs, including miR-206, miR-182-5p, and miR-766-3p, while liraglutide treatment had no significant effect on circulating miRNAs. These findings suggest that these drugs may have different influences on miRNA expression in individuals living with type 2 diabetes, and highlighting the need for further research to understand the underlying mechanisms, particularly regarding the impact of glimepiride on miRNA expression.
You-Bin Lee, So Hee Park, Kyu-na Lee, Bongsung Kim, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
Diabetes & Metabolism Journal 2023;47(5):682-692.
In this nationwide longitudinal study including 2,503,581 adults with T2DM, cumulative duration in low household income state (LHIS) was associated with an increased risk of mortality from pneumonia in a graded dose-response manner. Insulin users with the longest duration in LHIS were most vulnerable to death from pneumonia. These findings advance the argument that for adults with T2DM, strategies to prevent lethal pneumonia including vaccination, screening, care for comorbid respiratory diseases, and appropriate glycemic control should be offered more intensively to the low-income individuals, especially those using insulin, and policy-level interventions to mitigate disparities should be promoted.
Jun Suh Lee, Minji Sohn, Kyuho Kim, Yoo-Seok Yoon, Soo Lim
Diabetes & Metabolism Journal 2023;47(5):703-714.
In this prospective observational study, the difference in glucose dysregulation after pancreaticoduodenectomy (PD) and distal pancreatectomy (DP) was investigated. 224 patients who received partial pancreatectomy underwent comprehensive assessment, including a 75g oral glucose tolerance test preoperatively, and 1, 12, and 52 weeks after surgery. The disposition index showed a sustained decrease after DP, as opposed to a transient decrease after PD. During follow-up, the DP group showed a higher incidence of new-onset DM and worsening of glucose regulation, compared to PD. Proactive surveillance of glucose dysregulation is advised, especially after DP.
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